borate + sodium chloride

**Borate + sodium chloride** is a combination of the inorganic salts borate (commonly as sodium borate, also known as borax) and sodium chloride (table salt)[2][3][9][10]. This combination does not correspond to a single, widely approved pharmaceutical entity, but it is used in multi-ingredient products, notably as a component in ophthalmic (eye) solutions and contact lens rinses, often alongside boric acid for its buffering, tonicity, and mild antiseptic properties[7]. **Mechanism of action:** - **Sodium borate (borate):** Acts as a buffer, helping to maintain pH, and demonstrates mild antiseptic and antifungal effects by disrupting microbial cell membranes[3][5]. - **Sodium chloride:** Provides isotonicity to solutions by matching the osmolarity of bodily fluids such as tears, and it maintains electrolyte balance[9]. This combination is used primarily for its physical-chemical properties rather than any synergistic pharmacologic activity. **Primary indication**: Used in products for eye care (e.g., contact lens solutions, ophthalmic irrigation) as a buffering, tonicity, and mild antiseptic agent[7].