bornaprine

Bornaprine is a synthetic anticholinergic (antimuscarinic) drug primarily indicated for the treatment of Parkinson's disease and related movement disorders such as parkinsonism, dyskinesia, akathisia, and hyperhidrosis[1][2][3][5][6]. It acts as a potent nonselective antagonist of muscarinic acetylcholine receptors—mainly M1 and M2 subtypes—thereby inhibiting the action of acetylcholine in the central and peripheral nervous systems[3][6][8]. This mechanism helps restore neurotransmitter balance in conditions like Parkinson's disease where dopamine deficiency leads to relative cholinergic overactivity. Bornaprine has demonstrated efficacy in reducing parkinsonian tremors and symptoms associated with excessive sweating (hyperhidrosis)[1][3][5]. The drug is well absorbed orally with a long half-life (~30 hours in humans), allowing for sustained therapeutic effects[3]. Its side effect profile is typical of anticholinergics (e.g., dry mouth, blurred vision)[8].

Brand names

Sormodrem

Other names

bornaprinebornaprine hydrochloridebornaptine