Drug intelligence / Profile preview

boron phosphate nanoparticle drug

Development stage
Preclinical
Lead developer
Neuboron Medical Group
Modality
Nanoparticles → Drug Delivery Systems
Administration
Intravenous, Intra-arterial, Convection-enhanced Delivery, Intratumoral
01

Overview

**Boron phosphate nanoparticle drug** is a preclinical boron carrier being developed by Neuboron Therapy System for boron neutron capture therapy in solid tumors as an expanded BNCT indication beyond currently established settings such as head and neck cancer and glioma. The agent is described as a nanoparticle formulation loaded with boron phosphate and designed to improve boron-10 delivery to tumor tissue through nanoparticle-mediated accumulation and intratumoral distribution. After boron delivery, therapeutic activity is intended to occur during neutron irradiation, where boron-10 captures neutrons and generates highly localized high-linear-energy-transfer radiation that selectively destroys tumor cells. This program appears to be part of Neuboron's next-generation BNCT drug portfolio and remains at the preclinical stage.

Other names
boron phosphate-loaded nanoparticlesBoron Phosphate Nanoparticlenext-generation boron drug

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