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Bovine Basic Gel is an inert topical vehicle formulation used as a placebo control in clinical trials, specifically in studies evaluating recombinant bovine basic fibroblast growth factor (rbFGF) gel. It is utilized in a randomized, double-blind, half-face controlled trial (NCT06516939) sponsored by Shanghai Dermatology Hospital to treat sensitive skin with persistent erythema. As a vehicle control, it lacks the active bFGF protein, which is a mitogenic polypeptide that promotes skin repair by binding to fibroblast growth factor receptors (FGFRs). The gel serves to establish a baseline for efficacy and safety comparisons against the active rbFGF treatment.
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