Drug intelligence / Profile preview

bovine FSH superagonist

Development stage
Unknown
Lead developer
Trophogen
Modality
Recombinant Proteins and Enzymes
Administration
Subcutaneous, Intramuscular
01

Overview

Bovine FSH superagonist is a recombinant protein analog of follicle-stimulating hormone (FSH) designed to activate the follicle-stimulating hormone receptor (FSHR) with enhanced potency and prolonged biological activity compared to standard pituitary-derived or recombinant FSH preparations. Developed by Trophogen and licensed to Zoetis for veterinary applications, the drug utilizes superagonist technology to stimulate ovarian follicular development and superovulation. It is being investigated for use in human reproductive medicine to treat infertility and in veterinary medicine to improve the efficiency of embryo transfer protocols in beef and dairy cattle. The molecule is engineered to have increased binding affinity and signaling efficacy at the FSH receptor, potentially allowing for reduced dosing frequency and improved clinical outcomes in assisted reproductive technologies.

Other names
recombinant bovine FSH superagonistrbFSH superagonistbFSH superagonistbovine FSH superagonist (animal)
02

Targets

FSHR (Follicle-stimulating hormone receptor)

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