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bovine leukemia virus vaccine
- Development stage
- Preclinical
- Lead developer
- SET Technology
- Modality
- Vaccines & Immunotherapeutics
- Administration
- Intramuscular, Subcutaneous
01
Overview
The bovine leukemia virus vaccine is a veterinary vaccine under development by SET Technology (SYTE.bio) for the prevention of bovine leukemia virus (BLV) infection in cattle. BLV is an oncogenic deltaretrovirus that infects B-lymphocytes, causing enzootic bovine leukosis (EBL), persistent lymphocytosis, and lymphosarcoma, leading to significant economic losses in the global dairy and beef industries. Developed using SYTE's proprietary non-viral synthetic biology platforms, the vaccine utilizes DNA or RNA technology to express viral antigens and stimulate a protective immune response without the biosafety risks associated with traditional live-attenuated or viral-vector vaccines.
02
Targets
BCR (Immunoglobulin G B Cell Receptor)γδ TCR (T-cell receptor)TLR3 (Toll-like receptor 3)TLR9 (Toll-like receptor 9)
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