Drug intelligence / Profile preview

BPM31510T

Development stage
Unknown
Lead developer
Berg
Modality
Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Hydrogel Systems → Drug Delivery Systems
Administration
Topical
01

Overview

BPM31510T is a topical pharmaceutical formulation containing ubidecarenone (Coenzyme Q10; CoQ10), developed by BPGbio for the treatment of epidermolysis bullosa (EB) and other rare diseases. It is designed to support wound healing in EB by targeting cellular and mitochondrial processes, specifically influencing key pathways involved in inflammation, cell proliferation, and tissue remodeling. The drug delivers CoQ10 directly to mitochondria in skin cells, leading to increased ATP generation and enhanced metabolic activity in fibroblasts and keratinocytes. BPM31510T has demonstrated a favorable safety profile and potential efficacy for improving wound healing in early clinical trials. It has received both Orphan Drug Designation and Rare Pediatric Disease Designation from the FDA for EB[1][3][5][10].

Other names
BPM31510 topicalBPM-31510 topicalBPM 31510 topicalBPM31510 3% cream
02

Targets

OXPHOS (Mitochondrial OXPHOS complexes)

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