Drug intelligence / Profile preview

BR1018-1

Development stage
Phase 1
Lead developer
Boryung
Modality
Small Molecules
Administration
Oral
01

Overview

**BR1018-1** is an investigational Boryung drug product evaluated in a completed Phase 1 crossover study in healthy adults, both alone and in coadministration with BR1018-2. The study assessed pharmacokinetic interaction, safety, and tolerability in the context of hypertension and hyperlipidemia development. Public trial records do not disclose the precise active-ingredient composition, molecular target, dosage form, or mechanism specific to BR1018-1; it should not be conflated with the broader BR1018 hypertension and dyslipidemia development program.

02

Targets

NPC1L1 (Niemann-pick C1-Like 1 transporter)AGTR1 (Angiotensin II Type-1 receptor)HMGCR (3-hydroxy-3-methylglutaryl-coenzyme A reductase)LTCC (Voltage-gated calcium channel (L-type))

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