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Bria-OVA+ is a next-generation, personalized, off-the-shelf, cell-based immunotherapy candidate developed by BriaCell Therapeutics for the treatment of ovarian cancer. Built on the Bria-OTS+ platform, it is designed to engage and activate the immune system against tumor cells through multiple mechanisms, including CD40 ligand (CD40L) stimulation, CD80 stimulation, and CD86 inhibition. As a cellular biologic, it incorporates immune-stimulating components to enhance anti-tumor activity and provide a targeted approach to ovarian cancer treatment.
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