Clinical trials
Full profile accessFollow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
Brimonidine Drug Delivery System
- Development stage
- Unknown
- Lead developer
- Allergan
- Modality
- Small Molecules
- Administration
- Intravitreal
01
Overview
Brimonidine Drug Delivery System (Brimo DDS) is an investigational, biodegradable intravitreal implant developed by Allergan (an AbbVie company) for the treatment of geographic atrophy (GA) secondary to age-related macular degeneration and retinitis pigmentosa. The system utilizes a poly-(D,L-lactide) polymer matrix to provide sustained release of brimonidine tartrate (Generation 1) or brimonidine free base (Generation 2) into the vitreous over several months. Brimonidine is a selective alpha-2 adrenergic receptor agonist that exhibits neuroprotective properties by activating receptors on retinal neurons, potentially slowing the progression of retinal pigment epithelium (RPE) and photoreceptor loss. The implant is administered via a proprietary applicator system designed to deliver therapeutic levels of the drug directly to the posterior segment of the eye.
- Brand names
- Brimo PS DDS
- Other names
- Brimonidine Tartrate Posterior Segment Drug Delivery SystemBrimonidine Tartrate ImplantBrimonidine Intravitreal Implant
02
Targets
ADRA2A (α2A)ADRA2C (α2C)ADRA2B (α2B)
Beyond the preview
Go deeper on Brimonidine Drug Delivery System.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Full profile accessExplore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Full profile accessTrace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Full profile accessExplore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Full profile accessCompare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Full profile accessConnect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on Brimonidine Drug Delivery System.