Drug intelligence / Profile preview

Brinase

Development stage: Discontinued
Modality: Therapeutic Enzymes → Recombinant Proteins and Enzymes
Administration: Intravenous, Intra-arterial, Topical

Overview

Brinase (also known as brinolase) is a fibrinolytic enzyme and thrombolytic drug derived from the fungus *Aspergillus oryzae*. It acts by breaking down fibrin, a key protein involved in blood clot formation, thereby promoting the dissolution of clots. Brinase has been investigated for use in conditions where thrombolysis (clot breakdown) is desired, such as certain cardiovascular disorders.

Other names: brinolase

Targets

FGA (Fibrinogen alpha chain)Fibrin (Factor Ia)

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