Drug intelligence / Profile preview

broad spectrum cannabinoid formulation

Development stage
Phase 3
Lead developer
My Next Health
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

The broad spectrum cannabinoid formulation is a cannabis-derived investigational drug product containing the phytocannabinoids cannabidiol (CBD) and tetrahydrocannabinol (THC). Developed through a collaboration between the University of Regina and My Next Health Inc., the formulation is designed to target the endocannabinoid system to provide neuroprotective and anti-inflammatory benefits. It is primarily being evaluated for the prevention and treatment of concussions and post-concussion syndrome in athletes participating in contact sports, as well as for pain management as a potential alternative to opioids. The development program is notably supported by funding from the National Football League (NFL) and is currently being studied in a Phase II clinical trial (NCT06204003).

Other names
Naturally Produced Cannabinoidscannabinoid gel capsule
02

Targets

HTR1A (Serotonin receptor 1A (5-hydroxytryptamine receptor 1A))CNR1 (Cannabinoid receptor 1)CNR2 (Cannabinoid receptor type 2)Cyp (Cyclophilin family)FAAHGPR55 (G protein-coupled receptor 55)Glycine receptorPPARG (Peroxisome proliferator-activated receptor gamma)TRPA1 (Transient receptor potential cation channel subfamily A member 1)TRPV1 (Transient receptor potential cation channel subfamily V member 1)MOR (Mu opioid receptor)

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