brocresine

Brocresine is a small molecule inhibitor of histidine decarboxylase, the enzyme responsible for converting histidine to histamine. It was primarily studied as a tool compound for its effects on histamine biosynthesis in animal models, particularly in gastric mucosa[1][2][3][9]. The compound effectively inhibits histidine decarboxylase in vitro but exhibits poor or no inhibition in vivo when administered orally or intraperitoneally in rats[3]. Brocresine has no marketed indication and is considered an investigative or discovery agent[1][5].

Other names

brocresinbrocresina5-(aminooxymethyl)-2-bromophenol3-(aminooxymethyl)-6-bromphenolbrocresinum555-65-7alpha-(aminooxy)-6-bromo-m-cresolm-cresol, alpha-(aminooxy)-6-bromo-4-bromo-3-hydroxybenzyloxyaminephenol, 5-((aminooxy)methyl)-2-bromo-5-[(aminooxy)methyl]-2-bromophenolO-)4-brom-3-hydroxybenzyl)hydroxylaminQNWOSJAGFSUDFE-UHFFFAOYSA-NUNII-11F6O06WN0UNII11F6O06WN0UNII 11F6O06WN0BRN 1945736BRN1945736BRN-1945736