Drug intelligence / Profile preview

bromelain + papain + rutoside + trypsin

Development stage
Preclinical
Lead developer
Intra Life
Modality
Small Molecules, Recombinant Proteins and Enzymes, Peptides
Administration
Oral
01

Overview

Intramoto-XP is an oral fixed-dose combination tablet developed by Intra Life. It contains a synergistic blend of proteolytic enzymes—trypsin (96 mg), bromelain (180 mg), and papain (120 mg)—along with the antioxidant flavonoid rutoside trihydrate (200 mg). This combination is indicated for the treatment of inflammation, pain, swelling, and edema associated with musculoskeletal injuries, soft-tissue trauma, and post-operative or post-traumatic conditions. The proteolytic enzymes work by breaking down inflammatory proteins and debris at the site of injury, which improves blood flow and facilitates tissue repair. Rutoside acts as an antioxidant to strengthen blood vessels, reduce capillary permeability, and neutralize free radicals, thereby preventing further swelling and supporting the body's natural healing processes.

Brand names
Intramoto-XPIntramoto-XP TABS
Other names
Bromelain, Papain, Rutoside and TrypsinTrypsin + Bromelain + Rutoside + PapainTrypsin, Bromelain, Rutoside and PapainTrypsin, Bromelain, Rutoside, Papain
02

Targets

AKR1C3 (Aldo-keto reductase family 1 member C3)CBR1 (Carbonyl reductase 1)KNG1 (High-molecular-weight kininogen)MUC1 (Mucin-1 Antigen)MUC16 (Mucin-16)MUC4 (Mucin-4)MUC5AC (Mucin-5AC)MUC5B (Mucin-5B)TLR4 (Toll-like receptor 4)PAR2 (Protease-activated receptor 2)

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