bromopride

Bromopride is a substituted benzamide and dopamine antagonist with prokinetic and antiemetic properties, closely related to metoclopramide but distinguished by a bromine atom in place of chlorine. It acts primarily as a selective antagonist at dopamine D2 receptors in both the central nervous system and gastrointestinal tract, thereby inhibiting dopamine-mediated relaxation of the GI tract, enhancing gastric motility, accelerating gastric emptying, and reducing symptoms such as nausea and vomiting. Its clinical uses include treatment of nausea and vomiting—including postoperative nausea—gastroesophageal reflux disease (GERD), preparation for endoscopy or radiographic studies of the GI tract, hiccups, decreased appetite, flatulence when used in combination products, and management of gastrointestinal adverse effects from radiation therapy. It is generally well tolerated; common side effects include somnolence and fatigue; rare extrapyramidal symptoms may occur[1][2][4][6].

Brand names

DigesanPlaMetBromopridaBropinDigesigmaDigespridDigestalineDigestilDigestinaFágicoFurolLipolarModulanzimeOptimid DigestOranorexOraxialPridecilPrimet EnzimaticoSoftinValoprideYungprideProcirex

Other names

Bromopridum (Latin)Bromoprid (German)Bromopride (French)Bromoprida (Spanish)