bromopride + simethicone

Bromopride + simethicone is a fixed-dose combination of two agents used to manage gastrointestinal symptoms. Bromopride is a substituted benzamide and dopamine antagonist with prokinetic and antiemetic properties, closely related to metoclopramide. It acts primarily by blocking dopamine D2 receptor in the chemoreceptor trigger zone and enhancing gastrointestinal motility, making it effective for treating nausea, vomiting (including postoperative), gastroesophageal reflux disease (GERD), and as preparation for GI procedures[4][7]. Simethicone is an oral anti-foaming agent that relieves symptoms of excess gas such as bloating, pressure, or discomfort in the stomach and intestines. It works by reducing surface tension of gas bubbles in the gut, causing them to combine into larger bubbles that can be passed more easily[2][3][5]. The combination is used primarily for symptomatic relief of dyspepsia, flatulence, bloating, nausea/vomiting associated with functional GI disorders.

Other names

bromopride + simeticone