bromperidol

Bromperidol is a first-generation butyrophenone antipsychotic, structurally related to haloperidol. It acts primarily as a potent dopamine D2 receptor antagonist and is used in the treatment of schizophrenia and other psychotic disorders. The drug was discovered at Janssen Pharmaceutica in 1966. Bromperidol is available both as oral tablets and as a long-acting depot injection (bromperidol decanoate), with the latter used for maintenance therapy in several European countries. Its mechanism of action involves blocking dopamine D2 receptors, which helps reduce positive symptoms such as hallucinations and delusions[2][5][7]. Clinical trials have also explored its use for dementia, depression, anxiety disorders, and psychosomatic disorders[1][2].

Brand names

BromidolBromodolImpromenTesoprel

Other names

bromperidol