Drug intelligence / Profile preview

brompheniramine + pseudoephedrine

Development stage
Unknown
Modality
Small Molecules
Administration
Oral
01

Overview

**brompheniramine + pseudoephedrine** is a fixed-dose combination of two small molecule drugs used to relieve symptoms associated with the common cold, seasonal allergies, or other upper respiratory conditions. Brompheniramine is an antihistamine of the alkylamine class that acts as a histamine H1 receptor antagonist, reducing allergic responses such as sneezing, runny nose, and watery eyes. It also has anticholinergic (drying) and mild sedative effects. Pseudoephedrine is a sympathomimetic decongestant that acts primarily on alpha-adrenergic receptors in nasal mucosa to cause vasoconstriction, thereby reducing nasal congestion. The combination provides symptomatic relief but does not treat underlying infections[3][4][5].

Brand names
BrotappBromalineLodrane DEndafedTouro A and HBromadrine TRBromfedBromfed-PDBromfenexBromfenex PDBromuphedBromuphed PDBrovex SRDallergy-JRHistex SRIofedIofed PDLodraneLodrane 12 DLodrane12 DLodrane-12 DLodrane 24 DLodrane24 DLodrane-24 DLodrane LDLoHist-12DLoHist12DLoHist 12DPseubromPseubrom-PDRespahistTouroUltrabromUltrabrom PDUni-Tex[5][6]
Other names
brompheniramine and pseudoephedrine
02

Targets

ADRA1 (Alpha-1 adrenergic receptor family)HRH1 (Histamine H1 Receptor)

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