Drug intelligence / Profile preview

bronchogen

Development stage
Preclinical
Lead developer
St. Petersburg Institute of Bioregulation and Gerontology
Modality
Peptides, Small Molecules
Administration
Oral
01

Overview

Bronchogen is a synthetic tetrapeptide bioregulator (Ala-Glu-Asp-Leu) designed to support respiratory and lung health[4][6]. It acts by stabilizing DNA and modulating transcription factor activity in bronchial and lung tissues, enhancing cellular repair, reducing inflammation, improving surfactant production, and restoring epithelial integrity[2][4][5][6]. Developed primarily for prevention and adjunctive therapy of chronic bronchopulmonary diseases such as chronic bronchitis, COPD, and asthma, Bronchogen helps reduce coughing, bronchospasms, and supports immune defense in the lungs[1][2][3][5]. Its geroprotective properties may mitigate age-related decline in lung function, enhance resilience to environmental stressors, and modulate local immune responses (e.g., boosting secretory IgA levels)[4][5]. There are no significant side effects or addiction reported, but use during pregnancy or lactation is contraindicated.

Brand names
Bronchogen
Other names
BronchogenPeptide AKS-BACS-B bronchial peptideAla-Glu-Asp-Leu peptide
02

Targets

H3 (Histone H3.2)

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