broussonetia papyrifera extract

*Broussonetia papyrifera* extract, derived from the paper mulberry tree, is a botanical extract investigated for its anti-inflammatory, skin barrier-improving, and reproductive inhibitory properties. In dermatological research, specific fractions of the extract have been shown to inhibit inflammatory markers such as monocyte chemoattractant protein-1 (MCP-1) and CD86, while suppressing chemokine signaling pathways. Additionally, an alkaloid-rich fraction has been identified to activate the PPAR signaling pathway, promoting ceramide production and improving skin barrier function. Beyond skin health, the extract is being explored as a plant-based sterility agent for rodent population control, where it has demonstrated the ability to inhibit sex organ growth and reduce testosterone levels and sperm quality in male rodents.

Other names

paper mulberry extractBroussonetia papyrifera leaf methanol extractBroussonetia papyrifera ethanolic extract