Drug intelligence / Profile preview

Brozopentyl Sodium

Development stage
Phase 2
Lead developer
Ausun Pharmaceutical
Modality
Small Molecules
Administration
Intravenous
01

Overview

Brozopentyl Sodium (BZP) is a novel pharmaceutical agent under development for the treatment of ischemic stroke. Preclinical pharmacological studies have shown promising results, leading to its first-in-human investigation. The drug is administered via intravenous infusion and has demonstrated a good safety profile, tolerability, and predictable pharmacokinetic characteristics in healthy volunteers. It has a bioactive metabolite, BNBP.

Other names
布罗佐喷钠brozopentyl sodium注射用布罗佐喷钠
02

Targets

15-LOX (Lysyl Oxidase)IL1B (Interleukin-1 beta)TNFA (Tumor necrosis factor alpha (soluble))Kir (Inward-rectifier potassium channels)PLA2G4A (Cytosolic phospholipase A2 alpha)MAPK14 (p38 mitogen-activated protein kinase alpha)KCNK2 (Potassium channel subfamily K member 2)

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