Clinical trials
Follow clinical development from study design and recruitment through results.
- Trial phase
- Status
- Readouts
Drug intelligence / Profile preview
bryotoxin B
- Development stage
- Preclinical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Bryotoxin B is a specific bufadienolide compound isolated from the medicinal plant *Bryophyllum pinnatum* (also known as *Kalanchoe pinnata*). As a member of the bufadienolide class, it is structurally related to cardiac glycosides and is traditionally known for its potential cardiotonic and cytotoxic properties. Recent research, including in silico molecular docking studies, has highlighted its potential therapeutic utility in treating atherosclerosis. These studies suggest that bryotoxin B may act by targeting Adenosine monophosphate-activated protein kinase (AMPK) and Inducible nitric oxide synthase (iNOS), thereby potentially reducing the vascular inflammation and thickening associated with atherosclerotic disease. It is primarily studied as a bioactive constituent of herbal extracts in traditional Indonesian medicine.
- Other names
- bryotoxin B
02
Targets
AMPK (Adenosine monophosphate–activated protein kinase)NOS2 (Nitric Oxide Synthase 2)
Beyond the preview
Go deeper on bryotoxin B.
Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.
Indications & development
Explore development by indication, patient population, and geography.
- Indications
- Development status
- Countries
Licensing & deals
Trace asset ownership, licensing agreements, and commercial partnerships.
- Partners
- Deal terms
- Milestones
Patents & exclusivity
Explore the patent landscape and regulatory exclusivity around an asset.
- Patents
- Expiration dates
- Exclusivity
Competitive landscape
Compare development programs by target, modality, and indication.
- Competing assets
- Targets
- Development stage
Research & analysis
Connect source evidence and development news to your research questions.
- Publications
- News
- Analysis
Bring the full picture into focus.
See how Gosset can support your research on bryotoxin B.