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BS02
- Development stage
- Preclinical
- Lead developer
- Zhongke Aishen Pharmaceutical
- Modality
- Monoclonal Antibodies → Antibody-Based Therapeutics
- Administration
- Intravenous
01
Overview
BS02 is a monoclonal antibody biosimilar currently in preclinical development by Zhongke Aishen Pharmaceutical (also known as Amshenn). The drug is designed as a biosimilar to the marketed immune checkpoint inhibitor ipilimumab (Yervoy), targeting Cytotoxic T-lymphocyte protein 4 (CTLA-4). By blocking the interaction between CTLA-4 and its ligands (CD80/CD86), BS02 is intended to enhance T-cell activation and proliferation, thereby strengthening the immune response against tumor cells. The program is being developed for oncology indications, aiming to provide a therapeutic alternative with comparable efficacy and safety to the reference product.
- Other names
- HPV E6/E7 therapeutic vaccinedelNS-HPV E6/E7Blue Sky Vaccines HPV vaccine
02
Targets
CTLA-4 (Cytotoxic t-lymphocyte–associated protein 4)
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