Drug intelligence / Profile preview

BSC2100

Development stage
Preclinical
Lead developer
BiSiChem
Modality
Cytotoxic ADCs → Antibody-Drug Conjugates (ADCs) → Antibody Conjugates → Antibody-Based Therapeutics, Small Molecules
01

Overview

BSC2100 is a preclinical-stage small molecule agonist of the Stimulator of Interferon Genes (STING) pathway, currently under development by BiSiChem. STING is a critical mediator of the innate immune system; its activation leads to the production of Type I interferons and other pro-inflammatory cytokines, which can stimulate a robust T-cell-mediated anti-tumor response. BiSiChem is developing BSC2100 both as a standalone small molecule therapeutic and as a potent payload for antibody-drug conjugates (ADCs), aiming to provide targeted delivery of STING activation directly to the tumor microenvironment to enhance efficacy and reduce systemic toxicity.

02

Targets

STING (Stimulator of interferon genes protein)

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