Drug intelligence / Profile preview

BSP1

Development stage
Preclinical
Lead developer
Biosortia Microbiomics
Modality
Recombinant Proteins and Enzymes, Frozen FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Microbial Metabolites → Microbiome-Derived Products → Microbiome Therapeutics, Synthetic Biology Platforms → Engineered Microbial Therapeutics → Microbiome Therapeutics, Genetically Modified Bacteria → Engineered Microbial Therapeutics → Microbiome Therapeutics, Microbial Proteins → Microbiome-Derived Products → Microbiome Therapeutics, Peptides, Fresh FMT → Fecal Microbiota Transplantation (FMT) → Microbiome Therapeutics, Bacterial Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Complex Communities → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Yeast Strains → Single Strain Products → Live Biotherapeutic Products → Microbiome Therapeutics, Defined Consortia → Multi-strain Products → Live Biotherapeutic Products → Microbiome Therapeutics
01

Overview

"BSP1" is a non-specific designation that refers to several distinct biological entities with diverse functions and potential applications. These include: 1. **Black Soybean Peptide 1 (BSP1)**: A peptide derived from black soybeans, investigated for its neuroprotective effects against lead-induced neurotoxicity and Alzheimer's-related neuroinflammation. It acts by enhancing antioxidant activity and modulating key signaling pathways like RhoA/MAPK and AMPK/SIRT1. 2. **Bletilla striata Polysaccharide 1 (BSP1-1 or BSP1)**: A homogeneous polysaccharide extracted from the traditional Chinese medicinal herb *Bletilla striata*. It has shown promise in promoting wound healing in diabetic rats by reducing oxidative stress and enhancing angiogenesis and collagen deposition. It also plays a role in alleviating cadmium toxicity. 3. **Binder of Sperm Protein 1 (BSP1)**: A protein found in the seminal plasma of various mammals (e.g., bulls, rams, boars). It is crucial for sperm function, including motility, capacitation, and interaction with oocytes, and is considered a biomarker for male fertility. 4. **Bacillus subtilis strain BSP1**: A bacterial strain isolated from tobacco leaves, known for its ability to degrade proteins, which is relevant for improving tobacco leaf quality. 5. **Bone Sialoprotein 1 (BSP1)**: A gene/protein that serves as a marker for osteogenic differentiation, relevant in studies of bone regeneration and tissue engineering. 6. **Bsp1 (fungal CPI motif protein)**: A fungal protein identified in budding yeast, which regulates actin filament capping, a fundamental process in endocytosis and cytokinesis.

Other names
Black Soybean Peptide 1Bletilla striata Polysaccharide 1Binder of Sperm Protein 1Bacillus subtilis strain BSP1Bone Sialoprotein 1Bsp1 (fungal CPI motif protein)
02

Targets

HS (Heparan sulfate)

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