Drug intelligence / Profile preview

BST-104

Development stage
Phase 3
Lead developer
Braintropia
Modality
Classical Binding Small Molecules → Small Molecules, Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules
Administration
Oral
01

Overview

BST-104 is a standardized botanical extract derived from **Lonicera Flos**, the dried flower buds of *Lonicera japonica* (Japanese honeysuckle). Developed by the South Korean biotechnology company **Braintropia**, it is primarily investigated for the treatment of mild to moderate **functional dyspepsia** (FD). The extract is rich in bioactive polyphenols and flavonoids, such as chlorogenic acid and luteolin, which are thought to provide gastroprotective and anti-inflammatory benefits. BST-104 aims to alleviate common dyspeptic symptoms, including epigastric pain, bloating, and postprandial fullness, by protecting the gastric mucosa from oxidative stress and modulating inflammatory pathways. It has been evaluated in randomized, double-blind, placebo-controlled clinical trials in South Korea to establish its efficacy and safety profile as a natural therapeutic option for gastric disorders.

Other names
Lonicera Flos extractLonicera japonica extractJapanese honeysuckle extract

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