BST-InPod

BST-InPod is a drug-device combination product developed by Insulet Corporation for the treatment of opioid use disorder (OUD). It integrates the active pharmaceutical ingredient buprenorphine with Insulet's proprietary InPod technology, a wearable, automated subcutaneous delivery system originally derived from the OmniPod insulin pump. Buprenorphine functions as a partial agonist at the mu-opioid receptor and an antagonist at the kappa-opioid receptor, which helps to mitigate withdrawal symptoms and cravings while limiting the respiratory depression and euphoria associated with full opioid agonists. By utilizing a wearable pod for continuous subcutaneous administration, BST-InPod is designed to provide stable plasma concentrations of buprenorphine, potentially improving patient adherence and clinical outcomes compared to daily sublingual or periodic injectable formulations.

Other names

Buprenorphine InPodBuprenorphine Subcutaneous Therapy