Drug intelligence / Profile preview

BSVEQAb

Development stage
Unknown
Lead developer
Bharat Serums and Vaccines
Modality
Antibody-Based Therapeutics
Administration
Intravenous
01

Overview

BSVEQAb (Equine COVID-19 Antiserum) is an equine-derived polyclonal antibody product developed by Bharat Serums and Vaccines Limited (BSVL) for the treatment of COVID-19. The therapeutic consists of F(ab')2 fragments of equine polyclonal antibodies generated by immunizing horses with the SARS-CoV-2 spike protein. This biologic therapy is designed to provide passive immunization to COVID-19 infected patients, with the goal of neutralizing the virus, reducing viral load, and preventing disease progression. BSVL utilized its established expertise in equine biologicals—previously applied to anti-snake venom and anti-rabies treatments—to develop this product. It has been evaluated in Phase 1/2 clinical trials (NCT04834908) to assess safety and efficacy in RT-PCR positive patients.

Other names
Equine COVID-19 AntiserumEquine COVID-19 immune globulin GEquine COVID-19 Antiserum [F(ab')2]
02

Targets

SARS-CoV-2 spike

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