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BT810

Development stage: Preclinical
Lead developer: Base Therapeutics
Modality: Adenine Base Editors → Base Editing → Gene Editing → Gene Therapies, Cytosine Base Editors → Base Editing → Gene Editing → Gene Therapies

Overview

BT810 is an investigational gene therapy being developed by Base Therapeutics for the treatment of liver disease. The therapy utilizes the company's proprietary AccuBase base editing technology, which enables precise, single-nucleotide modifications to the genome without inducing double-strand DNA breaks. This approach is designed to address the underlying genetic drivers of liver pathology by either correcting pathogenic mutations or modulating gene expression. As of early 2024, the BT810 program is in the IND-enabling stage of development, with its specific molecular target currently undisclosed.

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