Drug intelligence / Profile preview

Budeplux

Development stage
Approved
Lead developer
Laboratorios Mallén
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation, Intranasal
01

Overview

Budeplux is a branded generic formulation of budesonide, a potent synthetic glucocorticoid with high local anti-inflammatory activity. Developed and marketed by Laboratorios Mallén, it is primarily indicated for the management of respiratory and allergic conditions, including bronchial asthma and allergic rhinitis. Budesonide functions as a glucocorticoid receptor agonist; upon binding, it inhibits the expression of multiple inflammatory genes and reduces the recruitment and activation of inflammatory cells such as mast cells, eosinophils, and lymphocytes. This action leads to a reduction in mucosal edema, airway hyperresponsiveness, and secretions, making it an effective maintenance therapy for chronic inflammatory airway diseases.

Brand names
Budeplux
Other names
Budesonida Mallén
02

Targets

GR (Glucocorticoid receptor)

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