Drug intelligence / Profile preview

budesonide + domperidone + omeprazole + salbutamol

Development stage
Unknown
Lead developer
AstraZeneca
Modality
Orthosteric Ligands → Classical Binding Small Molecules → Small Molecules
Administration
Inhalation, Oral, Intranasal, Rectal, Intravenous
01

Overview

This is a combination drug containing four active pharmaceutical ingredients: - Budesonide, a synthetic corticosteroid with potent glucocorticoid activity, primarily used to reduce inflammation in the airways. - Domperidone, a dopamine D2 receptor antagonist that acts as a prokinetic and antiemetic agent by enhancing gastrointestinal motility and blocking nausea/vomiting signals. - Omeprazole, a proton pump inhibitor (PPI) that suppresses gastric acid secretion by inhibiting the H+/K+ ATPase enzyme system in gastric parietal cells. - Salbutamol (also known as albuterol), a selective beta-2 adrenergic receptor agonist used as a bronchodilator to relieve bronchospasm in conditions such as asthma and chronic obstructive pulmonary disease (COPD). The combination of these agents would theoretically provide anti-inflammatory effects for airway diseases (budesonide), relief of bronchospasm (salbutamol), protection against gastrointestinal symptoms or reflux potentially associated with corticosteroid use or respiratory disease comorbidities (omeprazole), and management of nausea/gastrointestinal motility issues that may arise from polypharmacy or underlying illness (domperidone). There is no evidence this specific four-drug combination is marketed under any unique brand name; it appears to be an unbranded multi-drug regimen.

02

Targets

DRD3 (Dopamine receptor D3)GR (Glucocorticoid receptor)DRD2 (Dopamine D2 Receptor)ATP4A (Potassium–transporting ATPase alpha chain 1)ADRB2 (β2)

Beyond the preview

Go deeper on budesonide + domperidone + omeprazole + salbutamol.

Explore the evidence, development activity, and competitive landscape with Gosset’s full data platform.

Clinical trials

Full profile access

Follow clinical development from study design and recruitment through results.

  • Trial phase
  • Status
  • Readouts

Indications & development

Full profile access

Explore development by indication, patient population, and geography.

  • Indications
  • Development status
  • Countries

Licensing & deals

Full profile access

Trace asset ownership, licensing agreements, and commercial partnerships.

  • Partners
  • Deal terms
  • Milestones

Patents & exclusivity

Full profile access

Explore the patent landscape and regulatory exclusivity around an asset.

  • Patents
  • Expiration dates
  • Exclusivity

Competitive landscape

Full profile access

Compare development programs by target, modality, and indication.

  • Competing assets
  • Targets
  • Development stage

Research & analysis

Full profile access

Connect source evidence and development news to your research questions.

  • Publications
  • News
  • Analysis

Bring the full picture into focus.

See how Gosset can support your research on budesonide + domperidone + omeprazole + salbutamol.

Explore the full profile

Gosset Free

Get started with Gosset.

Enter your work email and we’ll be in touch with next steps.

Work email preferred.

Book a call