Drug intelligence / Profile preview

budesonide + salmeterol + azithromycin

Development stage
Preclinical
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Inhalation, Oral, Intravenous
01

Overview

This is a combination therapy consisting of budesonide (a corticosteroid), salmeterol (a long-acting beta-2 agonist), and azithromycin (a macrolide antibiotic). While not available as a single commercial product, similar combinations have been studied for respiratory conditions. Budesonide works by reducing inflammation in the airways, salmeterol acts as a bronchodilator by relaxing airway muscles, and azithromycin provides both antimicrobial and anti-inflammatory effects.

02

Targets

GR (Glucocorticoid receptor)Bacterial 50S ribosomal subunitADRB2 (β2)

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