Drug intelligence / Profile preview

budesonide + vitamin d

Development stage
Preclinical
Modality
Small Molecules
Administration
Inhalation, Oral
01

Overview

A combination therapy consisting of budesonide (a corticosteroid) and vitamin D (specifically vitamin D3 or cholecalciferol). Budesonide works by reducing inflammation through suppressing certain immune responses, while vitamin D plays roles in immune function regulation and may have protective effects on the respiratory tract. This combination has been studied for respiratory conditions including asthma and COPD, with research suggesting budesonide can up-regulate vitamin D receptor expression and enhance vitamin D's inhibitory effect on airway remodeling.

02

Targets

GR (Glucocorticoid receptor)VDR (Vitamin D receptor)

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