Drug intelligence / Profile preview

Budicort

Development stage
Phase 2
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Inhalation
01

Overview

Budicort is a brand name for budesonide, a potent synthetic corticosteroid with strong glucocorticoid activity and negligible mineralocorticoid effect. It is primarily used as an anti-inflammatory agent for the maintenance treatment of asthma and the prevention of asthma exacerbations. The drug is typically administered via inhalation using a Turbohaler device, which delivers the medication directly to the airways. Budesonide works by binding to and activating the glucocorticoid receptor, which subsequently modulates gene transcription to inhibit the production of inflammatory mediators such as cytokines, leukotrienes, and prostaglandins. This action reduces airway inflammation and bronchial hyperresponsiveness, helping to control symptoms and prevent attacks in patients with chronic respiratory conditions.

Brand names
Budicort
Other names
budesonide
02

Targets

GR (Glucocorticoid receptor)

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