bufei fang

Bufei Fang (补肺方), also known as the Bufei Jianpi formula or Bufei Jianpi Fang (补肺健脾方), is a traditional Chinese medicine (TCM) herbal combination primarily used for the treatment of chronic obstructive pulmonary disease (COPD). It is not a single chemical entity but a multi-herb decoction. The formula has demonstrated efficacy in improving pulmonary function and reducing lung inflammation in animal models of COPD. Mechanistically, it acts by modulating gut microbiota composition—specifically increasing Firmicutes and short-chain fatty acids—and suppressing inflammatory pathways such as the SCFAs/GPR43/NLRP3 axis. This results in improved mucosal immune function and reduced expression of pro-inflammatory cytokines like IL-8 and IL-1β[1][3]. The precise herbal composition may vary by source but typically includes herbs that tonify Qi, strengthen the spleen, and support lung health according to TCM theory.

Brand names

Bufei Jianpi granule

Other names

补肺方Bufei FangBufei Jianpi formula补肺健脾方