bupivacaine + dexamethasone (Ondokuz Mayıs University)

Group S refers to a specific treatment arm in a clinical trial (NCT05483400) conducted by Ondokuz Mayıs University, investigating the efficacy of different dexamethasone administration routes for postoperative pain management. In this protocol, patients receive a pericapsular nerve group (PENG) block using the local anesthetic bupivacaine, supplemented by a systemic (intravenous) dose of dexamethasone. Bupivacaine is a long-acting local anesthetic that functions by binding to and blocking voltage-gated sodium channels, thereby inhibiting nerve impulse generation and conduction. Dexamethasone, a potent synthetic glucocorticoid, is used as an adjuvant to prolong the duration of the sensory block and provide systemic anti-inflammatory effects, which helps in reducing postoperative pain scores and opioid consumption in patients undergoing femoral neck fracture surgery.

Other names

Group S-Ondokuz Mayıs University-postoperative painSystemic dexamethasone with PENG block