Drug intelligence / Profile preview

bupivacaine + methylprednisolone

Development stage
Unknown
Lead developer
AstraZeneca
Modality
Small Molecules
Administration
Epidural, Intramuscular, Local Injection, Infiltration
01

Overview

Bupivacaine + methylprednisolone is a combination medication used primarily for pain management. Bupivacaine is an amide local anesthetic that blocks nerve impulse generation and conduction through voltage-gated sodium channels, while methylprednisolone is a corticosteroid that reduces inflammation. This combination is commonly used for procedures like lumbar discectomy and treatment of low back pain, where it provides both anesthetic and anti-inflammatory effects.

Brand names
ReadySharp Anesthetics Plus Methylprednisolone 80Dyural 80 LDyural80 LDyural-80 L
Other names
methylprednisolone-Mayo Clinic-episodic migraineMethylprednisolone 40 MG InjectionMethylprednisolone40 MG InjectionMethylprednisolone-40 MG InjectionBupivacaine HCl 0.5% Injectable Solution
02

Targets

NaV (Voltage-gated sodium channels)GR (Glucocorticoid receptor)

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