Drug intelligence / Profile preview

bupleurum granules

Development stage
Unknown
Lead developer
Jiangsu Feima Pharmaceutical
Administration
Oral
01

Overview

Bupleurum granules (Chaihu Keli) is a Traditional Chinese Medicine (TCM) preparation developed and manufactured by Jiangsu Feima Pharmaceutical (also known as Jiangsu Pegasus Pharmaceutical). It is derived from the dried root of *Bupleurum chinense* DC. or *Bupleurum scorzonerifolium* Willd. The preparation is primarily used to treat symptoms associated with the common cold and influenza, such as fever, headache, and cough. In TCM theory, it is used to "resolve the exterior and clear heat" (解表散热), specifically targeting Shao Yang syndrome, which manifests as alternating chills and fever, chest fullness, and irritability. The active constituents include saikosaponins, which exhibit antipyretic, anti-inflammatory, and hepatoprotective properties. It is an approved pharmaceutical product in China, typically administered as an oral granule.

Other names
柴胡颗粒Chaihu KeliChai Hu Ke Li
02

Targets

NR1H3 (Liver X receptor beta)TLR4 (Toll-like receptor 4)

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