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Bushen Culuan Decoction + clomiphene citrate

Development stage: Unknown
Lead developer: Xiyuan Hospital
Modality: Small Molecules
Administration: Oral

Overview

A combination therapy consisting of Bushen Culuan Decoction (a traditional Chinese medicine formula) and clomiphene citrate (a Western ovulation induction medication). Bushen Culuan Decoction contains multiple Chinese herbs including Tusizi, Yinyanghuo, Xianmao, Xuduan, Gouqizi, Nvzhenzi, Zelan, Shengpuhuang, Xiangfu, and Chuanshanlong. According to traditional Chinese medicine theory, this combination works by tonifying the kidney, activating blood circulation, and promoting follicle maturation and ovulation. Clinical studies have shown this combination may increase pregnancy rates and improve hormone profiles in women with anovulatory infertility.

Targets

ESR2 (ERβ)ESR1 (ERα)

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