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Bushen Hemai Granules

Development stage: Unknown
Lead developer: Ruiyang Pharmaceutical
Modality: Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration: Oral

Overview

Bushen Hemai Granules is a Traditional Chinese Medicine (TCM) granule formulation developed by Ruiyang Pharmaceutical Co., Ltd. It is specifically indicated for the treatment of isolated systolic hypertension (ISH) in elderly patients. The therapeutic approach is rooted in TCM theory, focusing on tonifying the kidney ("Bushen") and harmonizing the blood vessels ("Hemai") to manage elevated systolic blood pressure. As of 2023, the drug is in Phase II clinical development in China (CTR20232754), with studies aimed at evaluating its safety and efficacy, as well as establishing the optimal dose and treatment course for future Phase III trials.

Brand names: Bushen Hemai Granules
Other names: 补肾和脉颗粒

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