Drug intelligence / Profile preview

Bushen Huatan Decoction

Development stage
Phase 2
Lead developer
Zhangjiagang Hospital of Traditional Chinese Medicine
Administration
Oral
01

Overview

Bushen Huatan Decoction (BSHTD) is a Traditional Chinese Medicine (TCM) herbal formula primarily used for the treatment of Polycystic Ovarian Syndrome (PCOS), specifically the subtype characterized by kidney deficiency and phlegm-dampness. The formula is designed to tonify the kidney Qi and resolve metabolic phlegm to restore endocrine balance and improve insulin sensitivity. It typically consists of a complex mixture of herbs, including *Cuscuta chinensis*, *Rehmannia glutinosa*, *Poria cocos*, and *Morinda officinalis*. Clinical research, largely conducted in China, evaluates BSHTD as a standalone therapy or in combination with Western pharmaceuticals like metformin and lifestyle interventions such as Baduanjin exercise to manage insulin resistance and reproductive dysfunction in PCOS patients.

Brand names
bu-shen hua-tan
Other names
Bushen Huatan TangKidney-Tonifying and Phlegm-Dispelling Prescription补肾化痰方补肾化痰汤Multi-sac I formula多囊I方
02

Targets

PIK3CA (Phosphoinositide 3-kinase alpha)AKT1 (Proto-oncogene serine/threonine-protein kinase Akt1)

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