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Bushen Huazhuo Formula

Development stage: Unknown
Lead developer: Xiyuan Hospital
Administration: Oral

Overview

Bushen Huazhuo Formula is a Traditional Chinese Medicine (TCM) herbal composition developed by Xiyuan Hospital of the China Academy of Chinese Medical Sciences. It is formulated based on the TCM principles of tonifying the kidney and resolving turbidity (Bushen Huazhuo) to address the underlying pathology of cognitive impairment. The formula is primarily investigated for the treatment of mild to moderate Alzheimer's disease and vascular dementia. Preclinical and clinical studies suggest that it may improve cognitive function by reducing amyloid-beta deposition, inhibiting tau protein hyperphosphorylation, and exerting anti-inflammatory and neuroprotective effects. It is typically administered as an oral granule.

Other names: Bushen Huazhuo decoctionBSHZFBushen Huazhuo granules

Targets

MAPT (Microtubule-associated protein tau)Aβ (Amyloid-beta peptides and aggregates)

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