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Bushen Huoxue Decoction
- Development stage
- Phase 1
- Lead developer
- Guang'anmen Hospital
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Bushen Huoxue Decoction is a Traditional Chinese Medicine (TCM) herbal formula developed by Guang'anmen Hospital of the China Academy of Chinese Medical Sciences. It is primarily indicated for the treatment of coronary heart disease (CHD) and stable angina pectoris, specifically targeting patients presenting with the TCM syndrome of kidney deficiency and blood stasis. The therapeutic rationale is based on the TCM principles of tonifying the kidney (Bushen) and promoting blood circulation to resolve stasis (Huoxue). It is currently being evaluated in multicenter, randomized, double-blind, placebo-controlled clinical trials to assess its efficacy in reducing angina frequency and improving cardiovascular function.
- Other names
- Bushen Huoxue TangBSHXD
02
Targets
EGFR (Epidermal growth factor receptor)ELANE (Human Neutrophil Elastase)MPO (Myeloperoxidase)PPARG (Peroxisome proliferator-activated receptor gamma)RXRA (Retinoid X receptor alpha)
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