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Bushen Huoxue Huatan granule
- Development stage
- Unknown
- Lead developer
- Changhai Hospital
- Administration
- Oral
01
Overview
Bushen Huoxue Huatan granule is a proprietary traditional Chinese medicine (TCM) formulation developed by The First Affiliated Hospital of Naval Medical University (also known as Shanghai Changhai Hospital) for the treatment of polycystic ovary syndrome (PCOS). The formulation is specifically designed for patients categorized under the TCM patterns of kidney deficiency and phlegm-dampness. It aims to restore hormonal balance and improve metabolic function by tonifying the kidney, promoting blood circulation to remove stasis, and resolving phlegm. In clinical trials, such as ChiCTR2000036470, the granule is evaluated both as a monotherapy and in combination with other interventions like acupoint catgut implantation and metformin to optimize treatment outcomes for PCOS-related symptoms, including menstrual irregularity and ovulatory dysfunction.
- Other names
- Bushen Huoxue Huatan formulaBushen Huoxue Huatan decoction
02
Targets
Insulin receptor / Insulin receptor substrate 1 signaling axisAR (Adrenergic receptors)
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