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Bushen Huoxue Yutai Formula
- Development stage
- Unknown
- Lead developer
- Shanghai University of Traditional Chinese Medicine
- Modality
- Implantable Devices → Device-based Delivery → Drug Delivery Systems, Small Molecules, Transdermal Patches → Device-based Delivery → Drug Delivery Systems, Inhalation Devices → Device-based Delivery → Drug Delivery Systems
- Administration
- Oral
01
Overview
Bushen Huoxue Yutai Formula is a traditional Chinese medicine (TCM) herbal combination used primarily to support reproductive health and treat gynecological and renal conditions. It is composed of multiple herbs with "Bushen" (tonifying the kidney), "Huoxue" (promoting blood circulation), and "Yutai" (nourishing the fetus or supporting pregnancy) actions. The formula has been studied for its effects in improving endometrial receptivity in women undergoing IVF by increasing endometrial blood flow and upregulating vascular endothelial growth factor expression[2][7]. It has also demonstrated efficacy in reducing renal fibrosis by inhibiting oxidative stress and NLRP3 inflammasome activation[1], as well as alleviating intervertebral disc degeneration through modulation of oxidative stress pathways[3]. Additionally, it may improve ovarian function via regulation of the Nrf2/Keap1 signaling pathway[5] and reduce pain intensity in lumbar disc herniation when combined with celecoxib[6].
- Brand names
- Bushen Huoxue Yutai Formula
- Other names
- BSHXFBSHX formulaBushen Huoxue formulaBSXHFBushen Yutai recipe
02
Targets
SMAD2 (Mothers against decapentaplegic homolog 2)NLRP3 (Nod-like receptor family pyrin domain-containing protein 3)
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