Drug intelligence / Profile preview

bushen quhan zhiwang decoction

Development stage
Unknown
Lead developer
China-Japan Friendship Hospital
Administration
Oral
01

Overview

Bushen Quhan Zhiwang decoction is a Traditional Chinese Medicine (TCM) herbal formula developed for the treatment of rheumatoid arthritis (RA), specifically for patients presenting with the "kidney deficiency and excessive cold" syndrome. The decoction is designed to tonify the kidneys, dispel cold, and alleviate joint pain (a condition referred to in TCM as Wang Bi). It is typically used as an adjunctive therapy alongside conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) like methotrexate to help patients achieve deep clinical remission. Clinical studies, including those led by the China-Japan Friendship Hospital and Peking University, evaluate its efficacy using disease activity scores (DAS28), pain scales (VAS), and mechanical pain threshold measurements.

Other names
Bushen Quhan Wang DecoctionBushen Quhan Zhiwang TangInib soup
02

Targets

RANKL (Receptor Activator for Nuclear Factor-kappa B Ligand)

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