Drug intelligence / Profile preview

bushenqiangduqinghuatang

Development stage
Unknown
Lead developer
China-Japan Friendship Hospital
Administration
Oral
01

Overview

Bushenqiangduqinghuatang is a Traditional Chinese Medicine (TCM) herbal decoction developed by the China-Japan Friendship Hospital for the treatment of ankylosing spondylitis (AS). The formula is designed based on TCM principles to tonify the kidney, strengthen the Du meridian, and clear damp-heat, addressing the core pathogenesis of AS in TCM theory. It is currently being evaluated in randomized controlled clinical trials to assess its clinical efficacy and safety, with a specific focus on its ability to inhibit pathological new bone formation, a hallmark of AS progression. The study utilizes serum biochemical markers of new bone formation to provide a scientific basis for its therapeutic effects.

Other names
Bushen Qiangdu Qinghua DecoctionBushen Qiangdu Qinghua Tang
02

Targets

IL1A (Interleukin 1 alpha)JNK (Mitogen-activated protein kinase kinase kinase family)IL-6 (Interleukin 6)MAPK3 (Mitogen-activated protein kinase 1)EGFR T790M (Epidermal growth factor receptor T790M mutant)VEGFA (Vascular endothelial growth factor A)

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