butylscopolamine bromide

Excosine (also marketed as Excosine-S) is a brand of butylscopolamine bromide (hyoscine butylbromide) developed and marketed by Quimica Son's in Mexico. Butylscopolamine bromide is a peripherally acting antimuscarinic, anticholinergic agent that acts as a competitive antagonist at muscarinic acetylcholine receptors (primarily M3 and M2 subtypes) on smooth muscle cells of the gastrointestinal, biliary, and genitourinary tracts. By blocking acetylcholine-mediated signaling, it reduces smooth muscle contractions and spasms, providing rapid relief from abdominal cramps, colic, and related pain. Because of its quaternary ammonium structure, it does not readily cross the blood-brain barrier, minimizing central nervous system side effects.

Brand names

ExcosineExcosine-S

Other names

bromuro de butilhioscinabutilhioscinabutylscopolaminebutylscopolamine bromidehyoscine butylbromidehyoscine N-butylbromideN-butylscopolammonium bromidescopolamine butylbromidescopolamine N-butylbromide