Drug intelligence / Profile preview

buxue yimu keli

Development stage
Phase 4
Lead developer
Tongji Hospital
Modality
Metabolically Activated Prodrugs → Prodrugs/Conditional Activator Small Molecules → Small Molecules, Classical Binding Small Molecules → Small Molecules
Administration
Oral
01

Overview

Buxue Yimu Keli is a Traditional Chinese Medicine (TCM) granule formulation primarily used for postpartum recovery. It is composed of several botanical extracts, typically including *Leonurus japonicus* (Motherwort), *Angelica sinensis* (Danggui), *Astragalus membranaceus* (Huangqi), *Paeonia lactiflora* (Baishao), and *Rehmannia glutinosa* (Dihuang). The formulation is designed to tonify blood and regulate menstruation, specifically addressing postpartum conditions such as anemia, lochia retention, and abdominal pain. Its therapeutic effects are attributed to its ability to promote uterine involution (contraction of the uterus) and stimulate hematopoiesis to improve red blood cell parameters. It is widely available in the Chinese pharmaceutical market and has been included in the Chinese Pharmacopoeia.

Brand names
Buxue Yimu Keli
Other names
Buxue Yimu Granules
02

Targets

AcetylcholinesteraseEPO (Erythropoietin)NOS2 (Nitric Oxide Synthase 2)IL-6 (Interleukin 6)PLA2G2A (Secretory phospholipase A2 group IIA)PLA2G4A (Cytosolic phospholipase A2 alpha)PDGFRB (Platelet-derived growth factor receptor beta)VEGFA (Vascular endothelial growth factor A)

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