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buxue yimu wan
- Development stage
- Phase 2
- Lead developer
- Zhuzhou Qianjin Pharmaceutical
- Modality
- Small Molecules
- Administration
- Oral
01
Overview
Buxue Yimu Wan is a traditional Chinese medicine formula composed of five herbal ingredients: Angelica sinensis (当归), Astragalus membranaceus (黄芪), Leonurus japonicus (益母草), Colla corii asini (阿胶), and Citrus reticulata (陈皮)[1][4]. It is widely used in China for the treatment of gynecological anemia and related conditions. The formula acts through multi-target mechanisms including regulation of inflammation, hormone balance, angiogenesis, hemostasis, response to hypoxia, immune modulation, and hematopoiesis[2][4]. Pharmacological studies have shown that it can increase red blood cell count and hemoglobin levels without significantly altering iron indices directly; its effects are attributed to optimized iron redistribution rather than increased absorption[2]. Network pharmacology has identified dozens of bioactive compounds in the formula—such as leonurine and astragaloside I—that act on targets involved in blood enrichment and immune enhancement[4].
- Brand names
- Buxue Yimu Wan
- Other names
- 补血益母丸Buxue Yimu PillsBYP
02
Targets
MMP2 (Matrix metalloproteinase-2)PLA2 (Phospholipase A2 group IID)PR (Progesterone receptor)AcetylcholinesteraseVEGFR2 (Vascular endothelial growth factor receptor 2)ESR1 (ERα)
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